Site-specific oxidative cleavage of DNA by metallosalen-DNA conjugates.

نویسندگان

  • Jennifer L Czlapinski
  • Terry L Sheppard
چکیده

Ni-salen-DNA conjugates, prepared by template-directed synthesis, targeted oxidative adduct formation and strand scission at deoxyguanosine sites in complementary DNA strands of Watson-Crick duplexes.

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عنوان ژورنال:
  • Chemical communications

دوره 21  شماره 

صفحات  -

تاریخ انتشار 2004